A new diamond biosensor with integrated graphitic microchannels for detecting quantal exocytic events from chromaffin cells.
نویسندگان
چکیده
An MeV ion-microbeam lithographic technique can be successfully employed for the fabrication of an all-carbon miniaturized cellular biosensor based on graphitic microchannels embedded in a single-crystal diamond matrix. The device is functionally characterized for the in vitro recording of quantal exocytic events from single chromaffin cells, with high sensitivity and signal-to-noise ratio, opening promising perspectives for the realization of monolithic all-carbon cellular biosensors.
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عنوان ژورنال:
- Advanced materials
دوره 25 34 شماره
صفحات -
تاریخ انتشار 2013